{
  "id": "https://uofa.net/morrison/validation/hemolysis-comparison-cou2",
  "type": "ValidationResult",
  "name": "Hemolysis prediction comparison (COU2 — absolute threshold)",
  "description": "CFD-predicted modified index of hemolysis (MIH) compared against in vitro hemolysis measurements at 5 flow-speed operating conditions. COU2 requires absolute threshold comparison (MIH < 0.1 g/100L) with Monte Carlo uncertainty quantification, unlike COU1 which uses relative predicate comparison.",
  "outcome": "pass",
  "wasDerivedFrom": "https://uofa.net/morrison/comparator/hemolysis-invitro",
  "wasGeneratedBy": {
    "id": "https://uofa.net/morrison/activity/hemolysis-comparison-cou2",
    "type": "VerificationActivity",
    "name": "COU2 hemolysis validation with UQ",
    "description": "Monte Carlo uncertainty quantification on hemolysis predictions. 1000 samples with perturbed inputs (blood properties, boundary conditions). 95% confidence intervals computed for MIH at each operating condition."
  },
  "comparedAgainst": {
    "id": "https://uofa.net/morrison/comparator/hemolysis-invitro",
    "type": "Comparator",
    "name": "In vitro hemolysis measurements",
    "description": "Modified index of hemolysis (MIH) measured from bovine blood experiments in the FDA generic blood pump at 5 operating conditions. Data collected by FDA OSEL."
  },
  "hasUncertaintyQuantification": {
    "id": "https://uofa.net/morrison/uq/monte-carlo-hemolysis-cou2",
    "type": "UncertaintyQuantification",
    "name": "Monte Carlo hemolysis UQ",
    "description": "1000-sample Monte Carlo propagation of input uncertainties (blood viscosity, inlet boundary conditions, hemolysis model constants) through CFD pipeline. 95% confidence intervals on predicted MIH at each of 5 operating conditions. This is the key structural difference from COU1, which has no UQ on hemolysis predictions."
  }
}